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SEPTEMBER 21 – 22, 2018 – FLORENCE


Novel optics-based approaches for cardiac

Relevance to future research and clinical intervention


2018 NOTICE Workshop

Research into cardiac electrophysiology in normal and pathological circumstances has been transformed by optics-based imaging methodologies. Recent innovations in optogenetic techniques allowed conditioned light to be used to modulate electrical activity in discrete parts of the heart. This meeting will bring together the leading proponents of novel optical techniques in Europe and the USA and discuss the major technical and biophysical questions they address.


The presentations and discussion will form the basis of a position paper on ‘Novel optics-based approaches for cardiac electrophysiology’ to be written after the meeting and supported by the European Society of Cardiology Working Group on Cellular Cardiac Electrophysiology (ESC WG on CCE).

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  • Paolo De Natale – National Institute of Optics, Italy
  • Corey Acker – UConn Health, US
  • Cecilia Ferrantini – University of Florence, Italy
  • Allen Kelly – University of Glasgow, UK
  • Leonardo Sacconi – National Institute of Optics, Italy
  • Stephan Lehnart – University of Gottingen, Germany
  • Camilla Parmeggiani – LENS, Italy
  • Godfrey Smith – University of Glasgow, UK
  • Corrado Poggesi – University of Florence, Italy

  • Francesco Pavone – LENS, Italy
  • Tobias Bruegmann – University of Bonn, Germany
  • Claudia Richter – MPI for Dynamics and Self-Organization, Germany
  • Marco Mongillo – University of Padova, Italy
  • Peter Kohl – University of Freiburg, Germany
  • Emilia Entcheva – The George Washington University, US
  • Gil Bub – McGill University, Canada
  • Elisabetta Cerbai – University of Florence, Italy
  • Tania Zaglia – University of Padova, Italy


Scientific Committee

  • Godfrey Smith
  • Leonardo Sacconi
  • Gil Bub
  • Marco Mongillo

Organizing Committee

  • Leonardo Sacconi
  • Godfrey Smith
  • Dobromir Dobrev
  • Camilla Parmeggiani
  • Lorenzo Pattelli
  • Daniele Martella
  • Marina Scardigli
  • Leonardo Cirri



Friday, September 21, 2018

  • 13:00 Welcome buffet
  • 14:00 Opening welcome

    Paolo De Natale, INO Director
    Francesco Pavone, LENS Director
    Leonardo Sacconi, Head of Cardiac Imaging Group, LENS and INO

  • 14:15 Introduction of the Workshop

    Godfrey Smith, University of Glasgow, UK

  • 14:30 Voltage imaging (Chairmen: Godfrey Smith, Gil Bub)

    • 14:30-15:00 Corey Acker
      Voltage sensitive dyes and techniques for optical voltage recordings from single cells to whole hearts
    • 15:00-15:30 Cecilia Ferrantini
      Optical dissection of T tubular electrophysiology
    • 14:30-15:00 Allen Kelly
      Going deeper with two-photon Transmural electrophysiology in the intact heart

  • 16:00 Coffee break
  • 16:30 Optoacoustics, super resolution and advanced materials (Chairmen: Cecilia Ferrantini, Dobromir Dobrev)

    • 16:30-17:00 Peter Kohl, Callum Zgierski-Johnston and Stefan Luther
      Cardiac electrophysiology beyond Einthoven: optoacoustic 3D ECG
    • 17:00-17:30 Stephan Lehnart
      Life at superresolution atria-specific Ca2+ signaling mechanisms
    • 17:30-18:00 Camilla Parmeggiani
      Light responsive smart materials: a new approach to muscular regeneration

  • 19:00 Aperitif at Villa Il Gioiello
  • 20:00 Social dinner at Trattoria Omero


Saturday, September 22, 2018

  • 8:30 Coffee
  • 09:00 Optogenetics vol. I (Chairmen: Elisabetta Cerbai, Leonardo Sacconi)

    • 09:00-09:30 Tobias Bruegmann
      Optogenetic defibrillation to investigate, improve and maybe even replace current defibrillation strategies
    • 09:30-10:00 Claudia Richter
      Shedding Light on Cardiac Dynamics From Low-Energy to Optogenetic Multi-Site Pacing Strategies
    • 10:00-10:30 Tania Zaglia
      A light kind of blue to understand muscle sympathetic neurons

  • 10:30 Coffee break
  • 11:00 Optogenetics vol. II (Chairmen: Corrado Poggesi, Marco Mongillo)

    • 11:00-11:30 Leonardo Sacconi
      Real-time optical manipulation of cardiac conduction in intact hearts
    • 11:30-12:00 Emilia Entcheva
      Optogenetics as an enabling tool for high-throughput electrophysiological studies
    • 12:00-12:30 Gil Bub
      All-optical control of cardiac excitation

  • 12:30 Relevance to future research and clinical intervention

    Godfrey Smith, University of Glasgow, UK
    Elisabetta Cerbai, University of Florence, Italy
    Corrado Poggesi, University of Florence, Italy

  • 13:00 Light lunch
  • 14:00 Round table on position paper and funding opportunities (invited participation only)

Register Now

The workshop is free of charge and registration include attendance to all sessions, conference material, lunches and coffee breaks. Due to limited availability please register as soon as possible by filling the form below. Social dinner is not included and can be paid on site.

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Registration is closed.
Thank you for your interest and for visiting the workshop webpage!

Travel Information

Venue: 21 September 2018

Sede Istituto Nazionale di Ottica, Arcetri
Largo Enrico Fermi 6, 50125 Firenze

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Venue: 22 September 2018

Villa il Gioiello, Arcetri
via del Pian dei Giullari 42, 50125 Firenze

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Galileo’s Briefings

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The first day of the workshop is also inserted in the Galileo’s Briefings series of meetings that the National Institute of Optics of the National Research Council organizes as an in-depth study on a specific topic dedicated to the scientific community or to the public audience.